Engineering Electron Transfer Flux between Cytochrome P450 Enzyme and P450 Reductase to Enhance Serotonin Production in Escherichia Coli
Abstract Microbial cell factories produce valuable compounds by exploiting cytochrome P450 catalytic systems. However, the inefficient electron transfer flux (ETF) between P450 and cytochrome P450 reductase (CPR) hinders the efficient synthesis of natural products. Herein, an ETF is systematically e...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-08-01
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| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202414859 |
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