gdf11 is required for pronephros/cloaca development through targeting TGF-β signaling

Abstract The kidney is a vital organ responsible for removing toxins, producing urine, and regulating homeostasis. Developmental defects in the kidney lead to various congenital abnormalities that impair renal function. Gdf11, a member of the transforming growth factor β family, is associated with n...

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Bibliographic Details
Main Authors: Xinning Tian, Wantao Yao, Jin Tan, Zhangle Hu, Jingwen Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-92571-y
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