Trivalent Phospha-Brook rearrangement enabled practical deoxygenative phosphonylation of carbonyls

Abstract Brønsted base-mediated [1,2]-phospha-Brook rearrangements have garnered considerable attention for developing new methodologies and efficiently constructing complex molecular structures. However, the strict reliance on pentavalent phosphonates imposes strong limitations on the reaction type...

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Bibliographic Details
Main Authors: Xiaoqiang Wu, Shanya Lu, Wei Zhong, Tao XU
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58990-1
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