Inhibition of Epithelial CC-Family Chemokine Synthesis by the Synthetic Chalcone DMPF-1 via Disruption of NF-κB Nuclear Translocation and Suppression of Experimental Asthma in Mice

Asthma is associated with increased pulmonary inflammation and airway hyperresponsiveness. The interaction between airway epithelium and inflammatory mediators plays a key role in the pathogenesis of asthma. In vitro studies evaluated the inhibitory effects of 3-(2,5-dimethoxyphenyl)-1-(5-methylfura...

Full description

Saved in:
Bibliographic Details
Main Authors: Revathee Rajajendram, Chau Ling Tham, Mohamad Nadeem Akhtar, Mohd Roslan Sulaiman, Daud Ahmad Israf
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/176926
Tags: Add Tag
No Tags, Be the first to tag this record!