Dissolving Microneedles Containing Lactoferrin Nanosuspension for Enhancement of Antimicrobial and Anti-Inflammatory Effects in the Treatment of Dry Eye Disease

Dissolving Microneedles Containing Lactoferrin Nanosuspension for Enhancement of Antimicrobial and Anti-Inflammatory Effects in the Treatment of Dry Eye Disease

<b>Background/Objectives:</b> Dry eye disease (DED), also known as “keratoconjunctivitis sicca”, is a common chronic ocular surface disease accompanied by inflammation and diminished tear production. Bovine Lactoferrin (BLF), a multi-functional iron-binding glycoprotein found in tears, d...

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Main Authors: Sammar Fathy Elhabal, Ahmed Mohsen Faheem, Sandra Hababeh, Jakline Nelson, Nahla A. Elzohairy, Suzan Awad AbdelGhany Morsy, Tassneim M. Ewedah, Ibrahim S. Mousa, Marwa A. Fouad, Ahmed Mohsen Elsaid Hamdan
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Pharmaceutics
Subjects:
dry eye disease (DED)
methicillin-resistant <i>Staphylococcus aureus</i> (<i>MRSA</i>)
Schirmer tear test
Draize test
nanosuspension
Online Access:https://www.mdpi.com/1999-4923/17/5/653
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