Evaluating Midazolam’s Influence on Bispectral Index and Propofol Concentrations Using Schnider and Eleveld Models in Target-Controlled Infusion General Anesthesia: A Prospective Observational Study

Evaluating Midazolam’s Influence on Bispectral Index and Propofol Concentrations Using Schnider and Eleveld Models in Target-Controlled Infusion General Anesthesia: A Prospective Observational Study

Background: Midazolam is widely used in clinical anesthesia, but its effects on the Bispectral Index (BIS) and propofol concentration at the effector site (CeP) are underexplored. This study investigates the pharmacodynamic interaction between midazolam and propofol in total intravenous anesthesia (...

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Bibliographic Details
Main Authors: Federico Linassi, Paolo Zanatta, Matthias Kreuzer, Emma Ciavattini, Christian Rizzetto, Michele Carron
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Life
Subjects:
intravenous anesthesia
infusion pump
bispectral index monitor
propofol
midazolam
anxiolytics
Online Access:https://www.mdpi.com/2075-1729/15/2/219
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