Dynamic alterations of circulating lymphocytes during the trajectory of Hantaan virus-induced hemorrhagic fever with renal syndrome

IntroductionHemorrhagic fever with renal syndrome (HFRS) is a zoonotic disease with high mortality. Almost 90% of global cases of HFRS are induced by Hantaan virus (HTNV) infection. Although lymphocyte dysfunction is a critical factor in HFRS progression, the specific immune dynamics of HTNV remain...

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Main Authors: Lin Su, Shuangjuan Liu, Lei Shi, Yuan Cheng, Juanjuan Gao, Ruirui Guo, Yinli He, Linpei Zhang, Tianyan Chen, Jinsong Hu, Xiaojiao Li, Yawen Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567306/full
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