Homocysteine promotes cardiomyocyte hypertrophy through inhibiting β-catenin/ FUNDC1 mediated mitophagy

Abstract Homocysteine can cause damage to cardiomyocytes. However, Mitophagy is essential for preserving homeostasis in cardiomyocytes. So, we focused on investigating the impact of homocysteine on cardiomyocyte mitophagy and cardiac hypertrophy through the β-catenin/FUNDC1 pathway. Mice were admini...

Full description

Saved in:
Bibliographic Details
Main Authors: Yanping Lei, Hengjing Hu, Huifang Tang, Hui Sun, Rui Liu, Yue Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-06772-6
Tags: Add Tag
No Tags, Be the first to tag this record!