Epigallocatechin-3-gallate inhibits osteogenic differentiation of vascular smooth muscle cells through the transcription factor JunB

Epigallocatechin-3-gallate inhibits osteogenic differentiation of vascular smooth muscle cells through the transcription factor JunB

Medial arterial calcification (MAC) accompanying chronic kidney disease (CKD) leads to increased vessel wall stiffness, myocardial ischemia, heart failure, and increased cardiovascular morbidity and mortality. Unfortunately, there are currently no drugs available to treat MAC. The natural polyphenol...

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Bibliographic Details
Main Authors: Li Tiantian, Fang Fei, Yin Hongmei, Zhang Zhen, Wang Xiangxiu, Wang Erxiang, Yu Hongchi, Shen Yang, Wang Guixue, He Weihong, Liu Xiaoheng
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-06-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
medial arterial calcification
chronic kidney disease
epigallocatechin-3-gallate
vascular smooth muscle cell
osteogenic differentiation
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024060
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