Exploring the Metabolism of Flubrotizolam, a Potent Thieno-Triazolo Diazepine, Using Human Hepatocytes and High-Resolution Mass Spectrometry

Exploring the Metabolism of Flubrotizolam, a Potent Thieno-Triazolo Diazepine, Using Human Hepatocytes and High-Resolution Mass Spectrometry

Background: The abuse of psychoactive substances presents challenges in clinical and forensic toxicology. The emergence of novel and potent drugs that pose significant health risks, in particular towards frequent abusers and users unaware of the ingredients, further complicates the situation. Design...

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Bibliographic Details
Main Authors: Prince Sellase Gameli, Johannes Kutzler, Diletta Berardinelli, Jeremy Carlier, Volker Auwärter, Francesco Paolo Busardò
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Metabolites
Subjects:
designer benzodiazepine
new psychoactive substances
metabolism
high-resolution mass spectrometry
biomarker
Online Access:https://www.mdpi.com/2218-1989/14/9/506
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