Human Endogenous Retroviruses as Novel Therapeutic Targets in Neurodegenerative Disorders

Human Endogenous Retroviruses as Novel Therapeutic Targets in Neurodegenerative Disorders

Human Endogenous Retroviruses comprise approximately 8% of the human genome, serving as fragments of ancient retroviral infections. Although they are generally maintained in a silenced state by robust epigenetic mechanisms, specific HERV groups, particularly HERV-W and HERV-K, can become derepressed...

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Bibliographic Details
Main Authors: Elena Rita Simula, Seyedesomaye Jasemi, Davide Cossu, Milena Fais, Ilaria Cossu, Vanna Chessa, Mattia Canu, Leonardo Antonio Sechi
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Vaccines
Subjects:
HERVs
amyotrophic lateral sclerosis
multiple sclerosis
Alzheimer′s disease
Parkinson′s disease
neurodegeneration
Online Access:https://www.mdpi.com/2076-393X/13/4/415
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