DNA probe pulldown screening uncovers O-GlcNAcylation modulation of transcription factor DNA interactions

DNA probe pulldown screening uncovers O-GlcNAcylation modulation of transcription factor DNA interactions

Abstract O-linked β-N-acetylglucosamine (O-GlcNAc), a critical post-translational modification predominantly found in the nucleus, plays a substantial role in regulating gene expression by modulating transcription factors (TFs) activity. However, quantitative analysis investigating the influence of...

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Bibliographic Details
Main Authors:	Guofang Li, Fanxu Meng, Xiaomin Zhong, Kairan Yu, Nana Zhang, Keren Zhang, Huang Huang, Wenli Li, Jianing Zhang, Wei Wang, Yan Ren, Yubo Liu
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-07-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-025-07074-7
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