DNA probe pulldown screening uncovers O-GlcNAcylation modulation of transcription factor DNA interactions

Abstract O-linked β-N-acetylglucosamine (O-GlcNAc), a critical post-translational modification predominantly found in the nucleus, plays a substantial role in regulating gene expression by modulating transcription factors (TFs) activity. However, quantitative analysis investigating the influence of...

Full description

Saved in:
Bibliographic Details
Main Authors: Guofang Li, Fanxu Meng, Xiaomin Zhong, Kairan Yu, Nana Zhang, Keren Zhang, Huang Huang, Wenli Li, Jianing Zhang, Wei Wang, Yan Ren, Yubo Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-07074-7
Tags: Add Tag
No Tags, Be the first to tag this record!