The C-type lectin receptor Dcir (Clec4a2) restrains Aspergillus fumigatus elimination by limiting the degranulatory activity of neutrophils

The C-type lectin receptor Dcir (Clec4a2) restrains Aspergillus fumigatus elimination by limiting the degranulatory activity of neutrophils

IntroductionC-type lectin receptors (CLRs) are innate sensors crucial for antifungal and antimycobacterial responses, contributing to host defenses against pathogens, including the ubiquitous mold Aspergillus fumigatus. Dendritic cell immunoreceptor (Dcir) modulates immune responses by limiting the...

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Bibliographic Details
Main Authors: Fabio Seiti Yamada Yoshikawa, Rikio Yabe, Shota Torigoe, Sho Yamasaki, Shinobu Saijo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
Dcir
Clec4a2
Aspergillus fumigatus
neutrophils
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1639400/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1639400/full

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