RGS14 promotes the progression of hepatocellular carcinoma by activating the cAMP/PKA/CREB signaling pathway

Abstract Background G protein-coupled receptors (GPCRs) mediate the intracellular signals that drive tumor development. Regulator of G protein signaling 14 (RGS14), a key negative regulator of GPCR signaling, influences liver injury, fat metabolism, and inflammation. However, the role of RGS14 in he...

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Bibliographic Details
Main Authors: Xiangnan Liang, Bin Xu, Qiuxiang Wang, Kai Gong, Chun Han, Binwen Sun, Kexin Ma, Liming Wang
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Journal of Cancer Research and Clinical Oncology
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Online Access:https://doi.org/10.1007/s00432-025-06212-y
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