Quantitative effect of scaffold abundance on signal propagation

Abstract Protein scaffolds bring together multiple components of a signalling pathway, thereby promoting signal propagation along a common physical ‘backbone’. Scaffolds play a prominent role in natural signalling pathways and provide a promising platform for synthetic circuits. To better understand...

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Bibliographic Details
Main Authors: Stephen A Chapman, Anand R Asthagiri
Format: Article
Language:English
Published: Springer Nature 2009-10-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2009.73
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