Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease
Niemann-Pick type C disease is an autosomal recessive storage disorder, characterized by abnormal sequestration of unesterified cholesterol within the late endolysosomal compartment of cells and accumulation of gangliosides and other sphingolipids. Progressive neurological deterioration and insurgen...
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Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2016-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2016/3830424 |
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