Stromal vascular fraction inhibits renal fibrosis by regulating metabolism and inflammation in obstructive nephropathy

Stromal vascular fraction inhibits renal fibrosis by regulating metabolism and inflammation in obstructive nephropathy

Obstructive nephropathy is one of the leading causes of kidney injury and fibrosis, which can lead to end-stage renal disease (ESRD). Stromal vascular fraction (SVF), a heterogeneous cell mixture derived from adipose tissue, has been widely used for regenerative medicine across many preclinical mode...

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Bibliographic Details
Main Authors: Guang Yue, Yunjie Yang, Hongshuai Jia, Yangyang Wu, Lifei Ma, Xiaoyu Yi, Yuandong Tao, Huixia Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
SVF
obstructive nephropathy
renal fibrosis
inflammation
PPAR
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1559446/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1559446/full

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