Hippocampal volumes in UK Biobank are associated with APOE only in older adults

Abstract INTRODUCTION The hippocampus atrophies with age and is implicated in neurodegenerative disorders including Alzheimer's disease (AD). We examined the interplay between age and apolipoprotein E (APOE) genotype on total hippocampal volume. METHODS Using neuroimaging data from 37,463 UK Bi...

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Main Authors: Ariya Chaloemtoem, Vera Thornton, Yoonhoo Chang, Andrey P. Anokhin, Michaël E. Belloy, Janine Bijsterbosch, Brian A. Gordon, Sarah M. Hartz, Laura J. Bierut
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
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Online Access:https://doi.org/10.1002/dad2.70024
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