Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease

Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease

IntroductionThe gut microbiota composition and the expression profiles of microRNAs (miRNAs) in the brain tissue, cerebrospinal fluid, and blood of patients with Alzheimer’s disease (AD) differ significantly from those with normal cognition function. The study aimed to initially explore the relation...

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Bibliographic Details
Main Authors: Kaihao Lin, Wenxia Lin, Zhikai Guo, Cuihong Chen, Liang Chen, Xianbin Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer’s disease
cognitive impairment
exosomal miRNA
gut microbiota
metagenomic sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1545690/full
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https://www.frontiersin.org/articles/10.3389/fnins.2025.1545690/full

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