A Patient with a Right Atrium Mass and Congenital Heart Disease: A Challenging Diagnosis of a Stubborn Disease

Cardiac lymphoma is extremely rare. An intracardiac mass has rarely been reported to be the cardiac involvement of extranodal lymphoma. It is difficult to establish a final diagnosis via routine examinations. The ability of an echocardiogram to characterize tissue is limited; systemic (18)F-FDG PET/...

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Main Authors: Wenyan Wang, Huaicong Long, Zhiying Zhao
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2016/6810961
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author Wenyan Wang
Huaicong Long
Zhiying Zhao
author_facet Wenyan Wang
Huaicong Long
Zhiying Zhao
author_sort Wenyan Wang
collection DOAJ
description Cardiac lymphoma is extremely rare. An intracardiac mass has rarely been reported to be the cardiac involvement of extranodal lymphoma. It is difficult to establish a final diagnosis via routine examinations. The ability of an echocardiogram to characterize tissue is limited; systemic (18)F-FDG PET/CT scans provide important information for both staging and response assessment in patients with lymphoma. A 68-year-old Chinese male with a second patent foramen ovale (PFO) and an interventricular septal defect presented at our institute with persistent fever, shortness of breath, repeated paroxysmal supraventricular tachycardia (PSVT) attack, and rapidly progressing superior vena cava syndrome. The patient also presented with a mass located in the upper right atrium and superior vena cava which was detected by echocardiogram. (18)F-FDG PET/CT scan revealed a pathological increase of (18)F-FDG uptake in the atrial mass and several other extracardiac lymph nodes. Lymph node biopsy was positive for large B-cell lymphoma. Immunohistochemistry revealed intense and diffuse expression of CD20, CD10, BCL-6, and Ki-67. The patient died without any chemotherapy 18 days after hospital discharge.
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spelling doaj-art-33dc0ba94d9e4d2eaf5c33f7e3f8e87c2025-02-03T01:27:09ZengWileyCase Reports in Cardiology2090-64042090-64122016-01-01201610.1155/2016/68109616810961A Patient with a Right Atrium Mass and Congenital Heart Disease: A Challenging Diagnosis of a Stubborn DiseaseWenyan Wang0Huaicong Long1Zhiying Zhao2Heart Failure Center, Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, ChinaGeriatric ICU, Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, ChinaGeriatric ICU, Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, ChinaCardiac lymphoma is extremely rare. An intracardiac mass has rarely been reported to be the cardiac involvement of extranodal lymphoma. It is difficult to establish a final diagnosis via routine examinations. The ability of an echocardiogram to characterize tissue is limited; systemic (18)F-FDG PET/CT scans provide important information for both staging and response assessment in patients with lymphoma. A 68-year-old Chinese male with a second patent foramen ovale (PFO) and an interventricular septal defect presented at our institute with persistent fever, shortness of breath, repeated paroxysmal supraventricular tachycardia (PSVT) attack, and rapidly progressing superior vena cava syndrome. The patient also presented with a mass located in the upper right atrium and superior vena cava which was detected by echocardiogram. (18)F-FDG PET/CT scan revealed a pathological increase of (18)F-FDG uptake in the atrial mass and several other extracardiac lymph nodes. Lymph node biopsy was positive for large B-cell lymphoma. Immunohistochemistry revealed intense and diffuse expression of CD20, CD10, BCL-6, and Ki-67. The patient died without any chemotherapy 18 days after hospital discharge.http://dx.doi.org/10.1155/2016/6810961
spellingShingle Wenyan Wang
Huaicong Long
Zhiying Zhao
A Patient with a Right Atrium Mass and Congenital Heart Disease: A Challenging Diagnosis of a Stubborn Disease
Case Reports in Cardiology
title A Patient with a Right Atrium Mass and Congenital Heart Disease: A Challenging Diagnosis of a Stubborn Disease
title_full A Patient with a Right Atrium Mass and Congenital Heart Disease: A Challenging Diagnosis of a Stubborn Disease
title_fullStr A Patient with a Right Atrium Mass and Congenital Heart Disease: A Challenging Diagnosis of a Stubborn Disease
title_full_unstemmed A Patient with a Right Atrium Mass and Congenital Heart Disease: A Challenging Diagnosis of a Stubborn Disease
title_short A Patient with a Right Atrium Mass and Congenital Heart Disease: A Challenging Diagnosis of a Stubborn Disease
title_sort patient with a right atrium mass and congenital heart disease a challenging diagnosis of a stubborn disease
url http://dx.doi.org/10.1155/2016/6810961
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