Targeting EZH2 in Cancer: Mechanisms, Pathways, and Therapeutic Potential

Enhancer of zeste homolog 2 (EZH2) is a methyltransferase involved in cell cycle regulation, cell differentiation, and cell death and plays a role in modulating the immune response. Although it mainly functions by catalyzing the tri-methylation of H3 histone on K27 (H3K27), to inhibit the transcript...

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Bibliographic Details
Main Authors: Maria Saveria Gilardini Montani, Rossella Benedetti, Mara Cirone
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/24/5817
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