Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis

Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis

ObjectiveThe present review was developed to critically evaluate the neuroprotective effects of edaravone for experimental rat models of spinal cord injury (SCI) and generalize the possible mechanisms.MethodsSystematic searches were carried out on databases including PubMed, Embase, Web of Science,...

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Bibliographic Details
Main Authors: Long-yun Zhou, Xiao-bo Wang, Xu-qing Chen, Ran Li, Bin-bin Yu, Meng-xiao Pan, Lu Fang, Jian Li, Xue-jun Cui, Min Yao, Xiao Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
edaravone
spinal cord injury
systematic review
neuroprotective effect
neurological function
action mechanism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1538879/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1538879/full

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