Association of Blood Donor-derived Cell-free DNA Levels With Banff Scores and Histopathological Lesions in Kidney Allograft Biopsies: Results From an Observational Study

Association of Blood Donor-derived Cell-free DNA Levels With Banff Scores and Histopathological Lesions in Kidney Allograft Biopsies: Results From an Observational Study

Background. Donor-derived cell-free DNA (dd-cfDNA) is an emerging biomarker of kidney allograft injury, mainly investigated in the context of rejection. However, the dd-cfDNA dynamics in other graft pathologies merit further investigation. Methods. In this single-center observational study, we prosp...

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Main Authors: Aylin Akifova, MD, Klemens Budde, MD, Mira Choi, MD, Kerstin Amann, MD, Maike Buettner-Herold, MD, Michael Oellerich, MD, Julia Beck, PhD, Kirsten Bornemann-Kolatzki, PhD, Ekkehard Schütz, PhD, Friederike Bachmann, MD, Fabian Halleck, MD, Eva V. Schrezenmeier, MD, Evelyn Seelow, MD, Bianca Zukunft, MD, Charlotte Hammett, MD, Nathan A. Pohl, Benedetta Mordà, MD, Jan Kowald, MD, Nils Lachmann, Diana Stauch, Bilgin Osmanodja, MD
Format: Article
Language:English
Published: Wolters Kluwer 2025-05-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001794
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http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001794

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