Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China

We collected data on feasibility and acceptability of a real-time web-linked adherence monitoring container among HIV-positive injection drug users (IDU) in China. “Wisepill” uses wireless technology to track on-time medication dosing. Ten patients on antiretroviral therapy (ART) at the Guangxi CDC...

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Main Authors: Mary Bachman DeSilva, Allen L. Gifford, Xu Keyi, Zhong Li, Cheng Feng, Mohamad Brooks, Mark Harrold, Hu Yueying, Christopher J. Gill, Xie Wubin, Taryn Vian, Jessica Haberer, David Bangsberg, Lora Sabin
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:AIDS Research and Treatment
Online Access:http://dx.doi.org/10.1155/2013/957862
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author Mary Bachman DeSilva
Allen L. Gifford
Xu Keyi
Zhong Li
Cheng Feng
Mohamad Brooks
Mark Harrold
Hu Yueying
Christopher J. Gill
Xie Wubin
Taryn Vian
Jessica Haberer
David Bangsberg
Lora Sabin
author_facet Mary Bachman DeSilva
Allen L. Gifford
Xu Keyi
Zhong Li
Cheng Feng
Mohamad Brooks
Mark Harrold
Hu Yueying
Christopher J. Gill
Xie Wubin
Taryn Vian
Jessica Haberer
David Bangsberg
Lora Sabin
author_sort Mary Bachman DeSilva
collection DOAJ
description We collected data on feasibility and acceptability of a real-time web-linked adherence monitoring container among HIV-positive injection drug users (IDU) in China. “Wisepill” uses wireless technology to track on-time medication dosing. Ten patients on antiretroviral therapy (ART) at the Guangxi CDC HIV clinic in Nanning, China, used Wisepill for one ART medication for one month. We monitored device use and adherence and explored acceptability of the device among patients. Mean adherence was 89.2% (SD 10.6%). Half of the subjects reported a positive overall experience with Wisepill. Seven said that it was inconvenient, supported by comments that it was large and conspicuous. Five worried about disclosure of HIV status due to the device; no disclosures were reported. Twelve signal lapses occurred (5.4% of prescribed doses), of which one was due to technical reasons, nine to behavioral reasons (both intentional and unintentional), and two to unclear reasons. Although the technical components must be monitored carefully, and acceptability to patients presents challenges which warrant further exploration, the Wisepill device has potential for adherence interventions that deliver rapid adherence-support behavioral feedback directly to patients, including IDU. The use of wireless technology appears uniquely promising for providing time-sensitive communication on patient behavior that can be harnessed to maximize the benefits of HIV treatment.
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spelling doaj-art-338bd2c29d7444cc8307e68a7d075bc82025-02-03T01:12:14ZengWileyAIDS Research and Treatment2090-12402090-12592013-01-01201310.1155/2013/957862957862Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in ChinaMary Bachman DeSilva0Allen L. Gifford1Xu Keyi2Zhong Li3Cheng Feng4Mohamad Brooks5Mark Harrold6Hu Yueying7Christopher J. Gill8Xie Wubin9Taryn Vian10Jessica Haberer11David Bangsberg12Lora Sabin13Center for Global Health and Development, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown, 3rd Floor, Boston, MA 02118, USADepartment of Health Policy and Management, Boston University School of Public Health, Talbot Building, T348W, Boston, MA 02118, USADitan Hospital, 13 Ditan Park, Andingmen Outer Street, Beijing 100011, ChinaFHI 360, Asia-Pacific Regional Office, 19th Floor, Tower 3, Sindhorn Building, 130-132 Wireless Road, Kwaeng Lumpini, Khet Phathumwan, Bangkok 10330, ThailandGlobal Health Strategies, Manila Room, 17th Floor, Ping an International Financial Plaza, Tower B, No. 1-3 Xinyuan South Road, Chaoyang District, Beijing 100022, ChinaCenter for Global Health and Development, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown, 3rd Floor, Boston, MA 02118, USACenter for Global Health and Development, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown, 3rd Floor, Boston, MA 02118, USAGuangxi CDC ART Clinic, 18 Jinzhou Road, Nanning, Guangxi 530028, ChinaCenter for Global Health and Development, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown, 3rd Floor, Boston, MA 02118, USAFHI 360, Asia-Pacific Regional Office, 19th Floor, Tower 3, Sindhorn Building, 130-132 Wireless Road, Kwaeng Lumpini, Khet Phathumwan, Bangkok 10330, ThailandCenter for Global Health and Development, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown, 3rd Floor, Boston, MA 02118, USACenter for Global Health, Massachusetts General Hospital, 100 Cambridge Street, 15th Floor, Boston, MA 02114, USACenter for Global Health, Massachusetts General Hospital, 100 Cambridge Street, 15th Floor, Boston, MA 02114, USACenter for Global Health and Development, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown, 3rd Floor, Boston, MA 02118, USAWe collected data on feasibility and acceptability of a real-time web-linked adherence monitoring container among HIV-positive injection drug users (IDU) in China. “Wisepill” uses wireless technology to track on-time medication dosing. Ten patients on antiretroviral therapy (ART) at the Guangxi CDC HIV clinic in Nanning, China, used Wisepill for one ART medication for one month. We monitored device use and adherence and explored acceptability of the device among patients. Mean adherence was 89.2% (SD 10.6%). Half of the subjects reported a positive overall experience with Wisepill. Seven said that it was inconvenient, supported by comments that it was large and conspicuous. Five worried about disclosure of HIV status due to the device; no disclosures were reported. Twelve signal lapses occurred (5.4% of prescribed doses), of which one was due to technical reasons, nine to behavioral reasons (both intentional and unintentional), and two to unclear reasons. Although the technical components must be monitored carefully, and acceptability to patients presents challenges which warrant further exploration, the Wisepill device has potential for adherence interventions that deliver rapid adherence-support behavioral feedback directly to patients, including IDU. The use of wireless technology appears uniquely promising for providing time-sensitive communication on patient behavior that can be harnessed to maximize the benefits of HIV treatment.http://dx.doi.org/10.1155/2013/957862
spellingShingle Mary Bachman DeSilva
Allen L. Gifford
Xu Keyi
Zhong Li
Cheng Feng
Mohamad Brooks
Mark Harrold
Hu Yueying
Christopher J. Gill
Xie Wubin
Taryn Vian
Jessica Haberer
David Bangsberg
Lora Sabin
Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China
AIDS Research and Treatment
title Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China
title_full Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China
title_fullStr Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China
title_full_unstemmed Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China
title_short Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China
title_sort feasibility and acceptability of a real time adherence device among hiv positive idu patients in china
url http://dx.doi.org/10.1155/2013/957862
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