The TB27 Transcriptomic Model for Predicting Mycobacterium tuberculosis Culture Conversion

The TB27 Transcriptomic Model for Predicting Mycobacterium tuberculosis Culture Conversion

Rationale: Treatment monitoring of tuberculosis patients is complicated by a slow growth rate of Mycobacterium tuberculosis. Recently, host RNA signatures have been used to monitor the response to tuberculosis treatment. Objective: Identifying and validating a whole blood-based RNA signature mode...

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Main Authors: Maja Reimann, Korkut Avsar, Andrew DiNardo, Torsten Goldmann, Gunar Günther, Michael Hoelscher, Elmira Ibraim, Barbara Kalsdorf, Stefan Kaufmann, Niklas Köhler, Anna Mandalakas, Florian Maurer, Marius Müller, Dörte Nitschkowski, Ioana Olaru, Cristina Popa, Andrea Rachow, Thierry Rolling, Helmut Salzer, Patricia Sanchez-Carballo, Maren Schuhmann, Dagmar Schaub, Victor Spinu, Elena Terhalle, Markus Unnewehr, Nika Zielinski, Jan Heyckendorf, Christoph Lange
Format: Article
Language:English
Published: Case Western Reserve University 2025-01-01
Series:Pathogens and Immunity
Subjects:
biomarker
therapy response
tuberculosis treatment
precision medicine
systems biology
Online Access:https://www.paijournal.com/index.php/paijournal/article/view/770
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