Cooperatively Catalyzed Activation of Thioglycosides with Iodine and Iron(III) Trifluoromethanesulfonate

Reported herein is a further expansion of the cooperatively catalyzed Koenigs–Knorr glycosylation reaction, known as “the 4K reaction”. It has been discovered that molecular iodine, along with a metal salt and an acid additive, can activate thioglycosides. Previous mechanistic studies showed the int...

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Bibliographic Details
Main Authors: Ashley R. Dent, Aidan M. DeSpain, Alexei V. Demchenko
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/30/15/3058
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