Navigating the unstructured by evaluating alphafold's efficacy in predicting missing residues and structural disorder in proteins.

The study investigated regions with undefined structures, known as "missing" segments in X-ray crystallography and cryo-electron microscopy (Cryo-EM) data, by assessing their predicted structural confidence and disorder scores. Utilizing a comprehensive dataset from the Protein Data Bank (...

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Bibliographic Details
Main Author: Sen Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0313812
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