The combination of SH003 and DTX induces cytotoxic cell infiltration in anti-PD1 resistant lung cancer

The combination of SH003 and DTX induces cytotoxic cell infiltration in anti-PD1 resistant lung cancer

Abstract The development of therapeutic strategies to overcome resistance to anti-PD1 therapies in lung cancer remains a significant challenge. Based on our recent findings of SH003’s immunomodulatory capabilities, this study investigates the combined effects of SH003 and docetaxel (DTX) as a potent...

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Bibliographic Details
Main Authors: Yu-Jeong Choi, Sang-Eun Lee, Daeun Kim, Hae-In Lim, Da Kyung Choi, Bong Kyu Park, Chan-Yong Jeon, Seong-Gyu Ko
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Cancer Immunology, Immunotherapy
Subjects:
SH003
Docetaxel
Combination treatment
Anti-PD1 resistance
Lung cancer
EGFR/JAK/STAT3 pathway
Online Access:https://doi.org/10.1007/s00262-025-04064-6
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https://doi.org/10.1007/s00262-025-04064-6

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