Transient destabilization of whole brain dynamics induced by N,N-Dimethyltryptamine (DMT)

Abstract The transition towards the brain state induced by psychedelic drugs is frequently neglected in favor of a static description of their acute effects. We use a time-dependent whole-brain model to reproduce large-scale brain dynamics measured with fMRI from 15 volunteers under 20 mg intravenou...

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Bibliographic Details
Main Authors: Juan Ignacio Piccinini, Yonatan Sanz Perl, Carla Pallavicini, Gustavo Deco, Morten Kringelbach, David Nutt, Robin Carhart-Harris, Christopher Timmermann, Enzo Tagliazucchi
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07576-0
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