The butyrate derived from probiotic Clostridium butyricum exhibits an inhibitory effect on multiple myeloma through cell death induction

The butyrate derived from probiotic Clostridium butyricum exhibits an inhibitory effect on multiple myeloma through cell death induction

Abstract Multiple myeloma (MM) is a hematological malignancy characterized by a poor prognosis. While certain probiotics have been shown to produce antitumor molecules that inhibit solid tumor progression, it remains unclear whether probiotic-derived compounds can exert similar effects on hematologi...

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Main Authors: Hiroaki Konishi, Takeshi Saito, Shuichiro Takahashi, Hiroki Tanaka, Katsuhiro Okuda, Hiroaki Akutsu, Tatsuya Dokoshi, Aki Sakatani, Keitaro Takahashi, Katsuyoshi Ando, Shin Kashima, Nobuhiro Ueno, Kentaro Moriichi, Naoki Ogawa, Mikihiro Fujiya
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-97038-8
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https://doi.org/10.1038/s41598-025-97038-8

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