Serum folate and homocysteine as biomarkers for suicide risk in major depressive disorder: insights in males and younger patients

Serum folate and homocysteine as biomarkers for suicide risk in major depressive disorder: insights in males and younger patients

Abstract Background Major depressive disorder (MDD) is a leading contributor to the global disease burden, with suicide constituting a critical complication. Current clinical assessment tools are limited by subjectivity and diagnostic delays, highlighting the urgent need for objective biomarkers to...

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Bibliographic Details
Main Authors: Anqi Zhang, Yuncong Qin, Han Wang, Nan Lyu, Qian Zhao, Ling Zhang, Juan Huang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Psychiatry
Subjects:
Folate
Homocysteine
Suicide
Major depressive disorder
Biomarker
Online Access:https://doi.org/10.1186/s12888-025-07183-7
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https://doi.org/10.1186/s12888-025-07183-7

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