Lysosome-Associated Membrane Protein Targeting Strategy Improved Immunogenicity of Glycoprotein-Based DNA Vaccine for Marburg Virus

Lysosome-Associated Membrane Protein Targeting Strategy Improved Immunogenicity of Glycoprotein-Based DNA Vaccine for Marburg Virus

Marburg hemorrhagic fever (MHF) is a fatal infectious disease caused by Marburg virus (MARV) infection, and MARV has been identified as a priority pathogen for vaccine development by the WHO. The glycoprotein (GP) of MARV mediates viral adhesion and invasion of host cells and therefore can be used a...

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Main Authors: Xiyang Zhang, Yubo Sun, Junqi Zhang, Hengzheng Wei, Jing Wang, Chenchen Hu, Yang Liu, Sirui Cai, Qinghong Yuan, Yueyue Wang, Yuanjie Sun, Shuya Yang, Dongbo Jiang, Kun Yang
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Vaccines
Subjects:
Marburg virus (MARV)
DNA vaccine
lysosome-associated membrane protein (LAMP)
Marburg hemorrhagic fever (MHF)
Online Access:https://www.mdpi.com/2076-393X/12/9/1013
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https://www.mdpi.com/2076-393X/12/9/1013

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