Prevalence of COVID-19 Vaccine Hesitancy Among Healthcare Workers in Nigeria: A Systematic Review and Meta-Analysis

ObjectiveThe purpose of this systematic review and meta-analysis was to determine the prevalence of COVID-19 vaccine hesitancy among Nigerian healthcare professionals.MethodsAn extensive language-unrestricted literature search was conducted across PubMed, Scopus, the Cochrane Library, and the Africa...

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Main Authors: Taagbara Jolly Abaate, Dabota Yvonne Buowari, Utchay A. Agiri, Tamunodiepiriye Inimgba, Vivian Ifeoma Ogbonna, Chizaram Onyeaghala, Glory Ovunda Worgu, Abiye Somiari, Emmanuella I. Ezebuiro, Ibe Arthur Onuah
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:International Journal of Public Health
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Online Access:https://www.ssph-journal.org/articles/10.3389/ijph.2025.1607655/full
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author Taagbara Jolly Abaate
Dabota Yvonne Buowari
Utchay A. Agiri
Tamunodiepiriye Inimgba
Vivian Ifeoma Ogbonna
Chizaram Onyeaghala
Glory Ovunda Worgu
Abiye Somiari
Emmanuella I. Ezebuiro
Ibe Arthur Onuah
author_facet Taagbara Jolly Abaate
Dabota Yvonne Buowari
Utchay A. Agiri
Tamunodiepiriye Inimgba
Vivian Ifeoma Ogbonna
Chizaram Onyeaghala
Glory Ovunda Worgu
Abiye Somiari
Emmanuella I. Ezebuiro
Ibe Arthur Onuah
author_sort Taagbara Jolly Abaate
collection DOAJ
description ObjectiveThe purpose of this systematic review and meta-analysis was to determine the prevalence of COVID-19 vaccine hesitancy among Nigerian healthcare professionals.MethodsAn extensive language-unrestricted literature search was conducted across PubMed, Scopus, the Cochrane Library, and the African Index Medicus to identify studies reporting hesitancy to COVID-19 vaccines among healthcare workers in Nigeria. Quality assessment was performed using the Newcastle-Ottawa scale for cross-sectional studies. A single-arm meta-analysis was performed using a random-effects model.ResultsOf the 206 articles, 22 publications with 20,724 participants were included. The pooled prevalence of COVID-19 vaccine hesitancy was 75% (95% CI: 61%–88%, I2 = 99.69%, P < 0.001). Reasons for hesitancy, including concerns about side effects, lack of trust, and safety, were prevalent at 76% (CI: 0.57–0.94, I2 = 99.24%, P < 0.001), 55% (CI: 0.042–0.272, I2 = 97.42%, P < 0.001), and 68% (CI: 0.047–0.89, I2 = 98.59%, P < 0.001), respectively.ConclusionThere was significant hesitancy among Nigerian healthcare workers towards COVID-19 vaccination; thus, strategies to increase vaccination acceptance among healthcare workers should be developed.
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spelling doaj-art-32fb5b9645634d2182905930bd32a5dc2025-02-05T09:52:10ZengFrontiers Media S.A.International Journal of Public Health1661-85642025-02-017010.3389/ijph.2025.16076551607655Prevalence of COVID-19 Vaccine Hesitancy Among Healthcare Workers in Nigeria: A Systematic Review and Meta-AnalysisTaagbara Jolly Abaate0Dabota Yvonne Buowari1Utchay A. Agiri2Tamunodiepiriye Inimgba3Vivian Ifeoma Ogbonna4Chizaram Onyeaghala5Glory Ovunda Worgu6Abiye Somiari7Emmanuella I. Ezebuiro8Ibe Arthur Onuah9Department of Community Medicine, University of Port Harcourt Teaching Hospital Nigeria, Port Harcourt, NigeriaDepartment of Accident and Emergency Medicine, University of Port Harcourt Teaching Hospital, Port Harcourt, NigeriaDepartment of Family Medicine, University of Port Harcourt Teaching Hospital, Port Harcourt, NigeriaDepartment of Community Medicine, University of Port Harcourt Teaching Hospital Nigeria, Port Harcourt, NigeriaDepartment of Community Medicine, University of Port Harcourt Teaching Hospital Nigeria, Port Harcourt, NigeriaDepartment of Internal Medicine, University of Port Harcourt Teaching Hospital, Port Harcourt, NigeriaDepartment of Community Medicine, University of Port Harcourt Teaching Hospital Nigeria, Port Harcourt, NigeriaDepartment of Community Medicine, University of Port Harcourt Teaching Hospital Nigeria, Port Harcourt, NigeriaDepartment of Obstetrics and Gynaecology, University of Port Harcourt Teaching Hospital, Port Harcourt, NigeriaDepartment of Surgery, University of Port Harcourt Teaching Hospital, Port Harcourt, NigeriaObjectiveThe purpose of this systematic review and meta-analysis was to determine the prevalence of COVID-19 vaccine hesitancy among Nigerian healthcare professionals.MethodsAn extensive language-unrestricted literature search was conducted across PubMed, Scopus, the Cochrane Library, and the African Index Medicus to identify studies reporting hesitancy to COVID-19 vaccines among healthcare workers in Nigeria. Quality assessment was performed using the Newcastle-Ottawa scale for cross-sectional studies. A single-arm meta-analysis was performed using a random-effects model.ResultsOf the 206 articles, 22 publications with 20,724 participants were included. The pooled prevalence of COVID-19 vaccine hesitancy was 75% (95% CI: 61%–88%, I2 = 99.69%, P < 0.001). Reasons for hesitancy, including concerns about side effects, lack of trust, and safety, were prevalent at 76% (CI: 0.57–0.94, I2 = 99.24%, P < 0.001), 55% (CI: 0.042–0.272, I2 = 97.42%, P < 0.001), and 68% (CI: 0.047–0.89, I2 = 98.59%, P < 0.001), respectively.ConclusionThere was significant hesitancy among Nigerian healthcare workers towards COVID-19 vaccination; thus, strategies to increase vaccination acceptance among healthcare workers should be developed.https://www.ssph-journal.org/articles/10.3389/ijph.2025.1607655/fullCOVID-19vaccine hesitancynon-acceptancehealthcare workersNigeria
spellingShingle Taagbara Jolly Abaate
Dabota Yvonne Buowari
Utchay A. Agiri
Tamunodiepiriye Inimgba
Vivian Ifeoma Ogbonna
Chizaram Onyeaghala
Glory Ovunda Worgu
Abiye Somiari
Emmanuella I. Ezebuiro
Ibe Arthur Onuah
Prevalence of COVID-19 Vaccine Hesitancy Among Healthcare Workers in Nigeria: A Systematic Review and Meta-Analysis
International Journal of Public Health
COVID-19
vaccine hesitancy
non-acceptance
healthcare workers
Nigeria
title Prevalence of COVID-19 Vaccine Hesitancy Among Healthcare Workers in Nigeria: A Systematic Review and Meta-Analysis
title_full Prevalence of COVID-19 Vaccine Hesitancy Among Healthcare Workers in Nigeria: A Systematic Review and Meta-Analysis
title_fullStr Prevalence of COVID-19 Vaccine Hesitancy Among Healthcare Workers in Nigeria: A Systematic Review and Meta-Analysis
title_full_unstemmed Prevalence of COVID-19 Vaccine Hesitancy Among Healthcare Workers in Nigeria: A Systematic Review and Meta-Analysis
title_short Prevalence of COVID-19 Vaccine Hesitancy Among Healthcare Workers in Nigeria: A Systematic Review and Meta-Analysis
title_sort prevalence of covid 19 vaccine hesitancy among healthcare workers in nigeria a systematic review and meta analysis
topic COVID-19
vaccine hesitancy
non-acceptance
healthcare workers
Nigeria
url https://www.ssph-journal.org/articles/10.3389/ijph.2025.1607655/full
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