A prospective, randomized, double-blind, placebo-controlled trial of the Kampo formula daiobotanpito combined with antibiotic therapy for acute diverticulitis

A prospective, randomized, double-blind, placebo-controlled trial of the Kampo formula daiobotanpito combined with antibiotic therapy for acute diverticulitis

Abstract Daiobotanpito (DBT) is a Kampo formula traditionally used to treat abscesses in intestinal disorders. This double-blind, multicenter, randomized controlled trial was conducted at participating hospitals in Japan. Patients with CT-proven moderate acute diverticulitis received conventional th...

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Main Authors: Keiko Ogawa-Ochiai, Shigetsugu Tsuji, Atsuki Maeda, Hisatomo Ikehara, Kazumi Kawabata, Takahiro Dohmen, Eisuke Ojima, Goro Nakayama, Takashi Hisabe, Masaya Suenaga, Takashi Kagaya, Kiyoshi Ishigure, Osamu Okochi, Masashi Hattori, Hirokazu Hirai, Toyotaka Kasai, Toshiya Takeda, Takanori Yamada, Isao Yoshida, Mitsuru Sakai, Akira Takehara, Yoshinori Munemoto, Mitsuru Esaki, Yoshinari Mochizuki, Koji Nishijima, Shinji Kitamura, Seisho Sakai, Takuo Hara, Li Honyang, Hisashi Doyama, Kunihisa Uchita, Yasuhiro Kodera, Kenichi Yoshimura, Keita Mori, Hideki Ishikawa
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Daiobotanpito, colon diverticulitis
Colonic diverticular disease
Abscess
Da Huang Mu Dan Tang
Japanese traditional medicine (Kampo)
Online Access:https://doi.org/10.1038/s41598-025-07385-9
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https://doi.org/10.1038/s41598-025-07385-9

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