Refining fine-mapping: Effect sizes and regional heritability.

Recent statistical approaches have shown that the set of all available genetic variants explains considerably more phenotypic variance of complex traits and diseases than the individual variants that are robustly associated with these phenotypes. However, rapidly increasing sample sizes constantly i...

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Bibliographic Details
Main Authors: Christian Benner, Anubha Mahajan, Matti Pirinen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011480
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