Controlling tumor progression and recurrence in mice through combined treatment with a PD-L1 inhibitor and a designer Salmonella strain that delivers GM-CSF

Controlling tumor progression and recurrence in mice through combined treatment with a PD-L1 inhibitor and a designer Salmonella strain that delivers GM-CSF

Combination therapy with checkpoint inhibitors blocks inhibitory immune cell signaling and improves clinical responses to anticancer treatments. However, continued development of innovative and controllable delivery systems for immune-stimulating agents is necessary to optimize clinical responses. H...

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Bibliographic Details
Main Authors: Heung Jin Jeon, Daejin Lim, EunA So, Solbi Kim, Jae-Ho Jeong, Miryoung Song, Hyo-Jin Lee
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Checkpoint inhibitor
Granulocyte macrophage colony stimulating factor
Programmed death-ligand 1
Salmonella
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383524002843
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