Hypocalcemia as a Cause of Complex Febrile Seizures in a Toddler

A 13-month-old boy had suffered three episodes of complex febrile seizures. At this admission, there were signs of hyperexcitability, such as Trousseau sign and QTc prolongation. A point of care blood gas analysis revealed severe hypocalcemia. Therefore, prior to administering intravenous calcium gl...

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Main Authors: Kevin Meesters, Tessa Wassenberg, Jesse Vanbesien
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2021/1798741
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author Kevin Meesters
Tessa Wassenberg
Jesse Vanbesien
author_facet Kevin Meesters
Tessa Wassenberg
Jesse Vanbesien
author_sort Kevin Meesters
collection DOAJ
description A 13-month-old boy had suffered three episodes of complex febrile seizures. At this admission, there were signs of hyperexcitability, such as Trousseau sign and QTc prolongation. A point of care blood gas analysis revealed severe hypocalcemia. Therefore, prior to administering intravenous calcium gluconate, we took blood samples to investigate the etiology of this hypocalcemia: magnesium, parathormone, and 25-hydroxyvitamin D. Since both parathormone and phosphate were significantly elevated and 25-hydroxyvitamin D was within the normal range, pseudohypoparathyroidism was diagnosed. After two years of follow-up, serum calcium had normalized in our patient under supplementation of vitamin D and calcium. He had been free of convulsions, although different febrile episodes had occurred.
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spelling doaj-art-32c1f06a046049aa95524e24992a9b592025-02-03T05:47:38ZengWileyCase Reports in Pediatrics2090-68032090-68112021-01-01202110.1155/2021/17987411798741Hypocalcemia as a Cause of Complex Febrile Seizures in a ToddlerKevin Meesters0Tessa Wassenberg1Jesse Vanbesien2Department of Pediatrics, KidZ Health Castle, Vrije Universiteit Brussel, Universitair Ziekenhuis Brussel, Laarbeeklaan 101, Brussels 1090, BelgiumPediatric Neurology Unit, KidZ Health Castle, Vrije Universiteit Brussel, Universitair Ziekenhuis Brussel, Laarbeeklaan 101, Brussels 1090, BelgiumDepartment of Pediatric Endocrinology, KidZ Health Castle, Vrije Universiteit Brussel, Universitair Ziekenhuis Brussel, Laarbeeklaan 101, Brussels 1090, BelgiumA 13-month-old boy had suffered three episodes of complex febrile seizures. At this admission, there were signs of hyperexcitability, such as Trousseau sign and QTc prolongation. A point of care blood gas analysis revealed severe hypocalcemia. Therefore, prior to administering intravenous calcium gluconate, we took blood samples to investigate the etiology of this hypocalcemia: magnesium, parathormone, and 25-hydroxyvitamin D. Since both parathormone and phosphate were significantly elevated and 25-hydroxyvitamin D was within the normal range, pseudohypoparathyroidism was diagnosed. After two years of follow-up, serum calcium had normalized in our patient under supplementation of vitamin D and calcium. He had been free of convulsions, although different febrile episodes had occurred.http://dx.doi.org/10.1155/2021/1798741
spellingShingle Kevin Meesters
Tessa Wassenberg
Jesse Vanbesien
Hypocalcemia as a Cause of Complex Febrile Seizures in a Toddler
Case Reports in Pediatrics
title Hypocalcemia as a Cause of Complex Febrile Seizures in a Toddler
title_full Hypocalcemia as a Cause of Complex Febrile Seizures in a Toddler
title_fullStr Hypocalcemia as a Cause of Complex Febrile Seizures in a Toddler
title_full_unstemmed Hypocalcemia as a Cause of Complex Febrile Seizures in a Toddler
title_short Hypocalcemia as a Cause of Complex Febrile Seizures in a Toddler
title_sort hypocalcemia as a cause of complex febrile seizures in a toddler
url http://dx.doi.org/10.1155/2021/1798741
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