Metabolomic profiling of plasma reveals differential disease severity markers in avian influenza A(H7N9) infection patients

Metabolomic profiling of plasma reveals differential disease severity markers in avian influenza A(H7N9) infection patients

Objectives: Avian influenza such as H7N9 is currently a major global public health risk, and at present, there is a lack of relevant diagnostic and treatment markers. Methods: We collected plasma samples from 104 confirmed H7N9 patients, 31 of whom died. Plasma metabolites were detected by UHPLC-HRM...

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Main Authors: Yuefeng Wang, Jili Ni, Mingzhu Huang, Wenxin Qu, Chang Liu, Zheying Mao, Jiaqi Bao, Weizhen Chen, Dongsheng Han, Fei Yu, Yifei Shen, Zhenzhen Deng, Shufa Zheng
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:International Journal of Infectious Diseases
Subjects:
H7N9
Metabolomic
Machine-learning
Death prediction model
Tryptophan metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S120197122500181X
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