Engineering bi-directional chemically-modulated synthetic condensates for cellular control

Abstract Biomolecular condensates are membraneless compartments involved in a wide range of cellular processes. Despite their fundamental role in the spatiotemporal regulation of cellular functions, tools for precisely manipulating phase-separated condensates remain limited, and effective methods fo...

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Bibliographic Details
Main Authors: Ni Zhen, Yue Yan, Guangya Zhu, Tianxin Zhu, Qi Zhang, Qi Chen, Yan Guo, Jidong Zhu, Qiuhui Pan, Jingjing Xie
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61877-w
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