Computational fluid dynamics of small airway disease in chronic obstructive pulmonary diseaseResearch in context

Computational fluid dynamics of small airway disease in chronic obstructive pulmonary diseaseResearch in context

Summary: Background: Small airways (<2 mm diameter) are major sites of airflow obstruction in chronic obstructive pulmonary disease (COPD). This study aimed to quantify the impact of small airway disease, characterized by narrowing, occlusion, and obliteration, on airflow parameters in smokers a...

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Main Authors: Yousry K. Mohamady, Vincent Geudens, Charlotte De Fays, Marta Zapata, Omar Hagrass, Lucia Aversa, Marie Vermant, Xin Jin, Lynn Willems, Iwein Gyselinck, Charlotte Hooft, Astrid Vermaut, Hanne Beeckmans, Pieterjan Kerckhof, Gitte Aerts, Celine Aelbrecht, Janne Verhaegen, Andrew Higham, Walter Coudyzer, Emanuela E. Cortesi, Arno Vanstapel, John E. McDonough, Marianne S. Carlon, Rozenn Quarck, Matthieu N. Boone, Lieven Dupont, Stephanie Everaerts, Dirk E. Van Raemdonck, Laurens J. Ceulemans, Tillie-Louise Hackett, Robin Vos, Yasser Abuouf, Joseph Jacob, Wim A. Wuyts, James C. Hogg, Marcel Filoche, Ghislaine Gayan-Ramirez, Wim Janssens, Bart M. Vanaudenaerde
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:EBioMedicine
Subjects:
Chronic obstructive pulmonary disease (COPD)
Small airway disease
Computational fluid dynamics (CFD)
Airway remodelling
Airway resistance
Obstruction
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425001148
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