Luteolin targets MKK4 to attenuate particulate matter-induced MMP-1 and inflammation in human keratinocytes

Abstract Particulate matter (PM) is an environmental pollutant that causes premature skin aging and inflammation. In the present study, we investigated the protective effects of luteolin, a bioactive flavonoid, against PM-induced skin damage in human keratinocytes (HaCaT cells). We examined the anti...

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Bibliographic Details
Main Authors: Jaehyeok Yun, Jong-Eun Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-01090-3
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