Label-free metabolic fingerprinting of motile mammalian spermatozoa with subcellular resolution

Abstract Background Sperm metabolic pathways that generate energy for motility are compartmentalized within the flagellum. Dysfunctions in metabolic compartments, namely mitochondrial respiration and glycolysis, can compromise motility and male fertility. Studying these compartments is thus required...

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Bibliographic Details
Main Authors: Fitore Kusari, Lenka Backova, Dalibor Panek, Ales Benda, Zdenek Trachtulec
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Biology
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Online Access:https://doi.org/10.1186/s12915-025-02167-1
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