ADAM23 in Cardiomyocyte Inhibits Cardiac Hypertrophy by Targeting FAK‐AKT Signaling

ADAM23 in Cardiomyocyte Inhibits Cardiac Hypertrophy by Targeting FAK‐AKT Signaling

Background Cardiac hypertrophy has been recognized as an important independent risk factor for the development of heart failure and increases the risk of cardiac morbidity and mortality. A disintegrin and metalloprotease 23 (ADAM23), a member of ADAM family, is involved in cancer and neuronal differ...

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Main Authors: Mei Xiang, Hongbo Luo, Jia Wu, Lingyun Ren, Xiangchao Ding, Chuangyan Wu, Jiuling Chen, Shanshan Chen, Hao Zhang, Lu Yu, Yanqiang Zou, Heng Xu, Ping Ye, Manhua Chen, Jiahong Xia
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
a disintegrin and metalloprotease23
Akt
cardiac hypertrophy
focal adhesion kinase
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.008604
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https://www.ahajournals.org/doi/10.1161/JAHA.118.008604

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