N-Acetylcysteine-Amide Protects Against Acute Acrylamide Neurotoxicity in Adult Zebrafish

N-Acetylcysteine-Amide Protects Against Acute Acrylamide Neurotoxicity in Adult Zebrafish

Acrylamide (ACR) is a potent neurotoxicant that disrupts cellular redox homeostasis by depleting reduced glutathione (GSH) and inducing oxidative stress. Despite its well-characterized mechanism, no effective treatments for ACR-induced neurotoxicity currently exist. This study evaluates the therapeu...

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Main Authors: Niki Tagkalidou, Júlia Goyenechea-Cunillera, Irene Romero-Alfano, Maria Olivella Martí, Juliette Bedrossiantz, Eva Prats, Cristian Gomez-Canela, Demetrio Raldúa
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Toxics
Subjects:
acrylamide
neurotoxicity
zebrafish model
glutathione
acoustic startle response
habituation
Online Access:https://www.mdpi.com/2305-6304/13/5/362
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https://www.mdpi.com/2305-6304/13/5/362

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