Protocol for the MERINO study: A randomized placebo-controlled trial assessing the efficacy, safety, and cost-effectiveness of methotrexate in people with erosive hand osteoarthritis

Protocol for the MERINO study: A randomized placebo-controlled trial assessing the efficacy, safety, and cost-effectiveness of methotrexate in people with erosive hand osteoarthritis

Objective: Previous studies on the efficacy of methotrexate in people with hand osteoarthritis (OA) have shown conflicting results. The MERINO trial aims to investigate the efficacy and safety of methotrexate in people with painful inflammatory erosive hand OA. Design: In total 163 participants with...

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Bibliographic Details
Main Authors: Alexander Mathiessen, Line Gaundal, Joseph Sexton, Dag Sjølie, Pernille Steen Pettersen, Barbara Slatkowsky-Christensen, Ida Kristin Haugen
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Methotrexate
Erosive hand osteoarthritis
Pain
Function
Imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913124001250
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