Up-and-down determination of prophylactic norepinephrine boluses combined with crystalloid co-load for preventing post-spinal anesthesia hypotension during cesarean section

Up-and-down determination of prophylactic norepinephrine boluses combined with crystalloid co-load for preventing post-spinal anesthesia hypotension during cesarean section

Abstract Background The use of a fluid co-load has been shown to enhance hemodynamic stability and diminish the occurrence of hypotension after spinal anesthesia when paired with prophylactic norepinephrine. This research aimed to identify the effective dosages (ED90 and ED50) of prophylactic norepi...

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Bibliographic Details
Main Authors: Chengfei Xu, Peipei Zhang, Chunying Dai, Jingjun Zhang, Honghao Wu, Qianying Liu, Zhiqiang Zhang, Fengwei Yin, Huadong Ni, Liang Cheng
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Anesthesiology
Subjects:
Crystalloid co-load
Norepinephrine
Post-spinal anesthesia hypotension
Cesarean section
Online Access:https://doi.org/10.1186/s12871-025-02913-6
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