Nanoparticle Uptake and Crossing by Human In Vitro Models of Intestinal Barriers: A Scoping Review

Nanoparticle Uptake and Crossing by Human In Vitro Models of Intestinal Barriers: A Scoping Review

The Caco-2 in vitro model of the intestinal barrier is a well-established system for the investigation of the intestinal fate of orally ingested chemicals and drugs, and it has been used for over ten years by pharmaceutical industries as a model for absorption in preclinical studies. The Caco-2 mode...

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Bibliographic Details
Main Authors: Chiara Ritarossi, Valentina Prota, Francesca De Battistis, Chiara Laura Battistelli, Isabella De Angelis, Cristina Andreoli, Olimpia Vincentini
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Series:Nanomaterials
Subjects:
in vitro intestinal barrier
human exposure
crossing
uptake
nanoparticles
new approach methodologies
Online Access:https://www.mdpi.com/2079-4991/15/15/1195
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