Immune suppressive activities of low-density neutrophils in sepsis and potential use as a novel biomarker of sepsis-induced immune suppression

Immune suppressive activities of low-density neutrophils in sepsis and potential use as a novel biomarker of sepsis-induced immune suppression

Abstract Data of low-density neutrophils (LDN), the neutrophils in the peripheral blood mononuclear cells (PBMC) fraction, in sepsis is still less. As such, LDN (CD66b-positive cells in PBMC) was highest in intensive care unit (ICU) patients with sepsis (n=24) compared with non-sepsis (n=10) and hea...

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Main Authors: Awirut Charoensappakit, Kritsanawan Sae‑khow, Nuntanuj Vutthikraivit, Patinya Maneesow, Thitiwat Sriprasart, Monvasi Pachinburavan, Asada Leelahavanichkul
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-92417-7
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https://doi.org/10.1038/s41598-025-92417-7

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