The role of the apoptosis-related protein BCL-B in the regulation of mitophagy in hepatic stellate cells during the regression of liver fibrosis

Abstract The clearance of activated hepatic stellate cells (HSCs) by apoptosis is critical for the reversibility of hepatic fibrosis. Mitochondrial homeostasis is regulated by mitophagy, which is an efficient way of clearing injured mitochondria that plays an important role in apoptosis. However, th...

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Bibliographic Details
Main Authors: Qian Ding, Xiao-Li Xie, Miao-Miao Wang, Jie Yin, Jin-Mei Tian, Xiao-Yu Jiang, Di Zhang, Jing Han, Yun Bai, Zi-Jin Cui, Hui-Qing Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0199-6
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